All 1960 Edsels were assembled at the Louisville, Kentucky, assembly plant. The line was reduced to the Ranger series of sedans, hardtops, and convertibles and the Villager station wagons. The Edsel shared a basic chassis, glass, and major sheet metal with the 1960 Ford models that were also built in the Louisville plant. However, the Edsel had its own unique grille, hood, and four upright oblong taillights, along with its side sweep spears. The Edsel's front and rear bumpers were also unique. The 1960 Edsel rode on a 120" wheelbase, versus the Ford's 119", and it also used a different rear suspension. The cars shared engines and transmissions.

The 1960 Edsel Ranger four-door hardtop model used the thin-pillar Ford Fairlane four-door sedan roofline, as opposed to the "square" roofline used on the corresponding Ford four-door hardtop. The Galaxie four-door hardtop's rear door trim panel was fitted to the Ranger, giving the Edsel a unique body style that was not offered on any 1960 Ford.

Ford announced the end of the Edsel program on Thursday, November 19, 1959. However, production continued until late in November, with the final tally of 2,846 1960 models.